I am fond of Gino’s East on Superior St.  It is a Chicago landmark.  I know that many roadfooders (one in particular) are devoted to Burt’s Place but I have never been there so I can’t comment.  If you’re staying in the Loop or on the Mag Mile Gino’s is much more convenient.  I am a fan of their sausage pizza with the whole patty of sausage that covers the entire pizza.  I have been going to Gino’s since I was a kid so it could be the nostalgia factor that clouds my judgement.  I have been to Lou Malnati’s and it is good but my favorite continues to be Gino’s.  Wherever you end up going ENJOY!